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Beyond Standard of Care

Repurposed Drugs

Existing medicines are being investigated for potential activity against glioblastoma. Evidence varies considerably and remains mostly preclinical or observational, so these drugs should only be considered with the treating physician.

Investigational

Standard treatment remains the essential foundation of glioblastoma care. However, glioblastoma is highly individual and difficult to control. Exploring additional treatment options may improve the chance of achieving a better outcome than standard treatment alone.

 

Discuss the possibilities with your treating physician and consider seeking a second opinion from a specialised neuro-oncology centre. The options below vary in their level of evidence and are not suitable for every patient, but they can support a more informed discussion about the next steps in your treatment.

Personalized Vaccines

Peptide, dendritic-cell or mRNA vaccines designed around tumor antigens.

Investigational

CeTeG Protocol

Lomustine plus temozolomide for selected patients with MGMT-methylated GBM.

Selected Patients - Alternative

Tumor Treating Fields

Non-invasive electric-field therapy added during maintenance treatment.

Established Addition

Exploring Advanced Treatments

  • 01.

    Clinical Trails

    Explore experimental treatments in structured research programs. Visit our dedicated Clinical Trials page for more information.

  • 02.

    Advanced Diagnostics

    Comprehensive molecular testing—including DNA sequencing, RNA sequencing and methylation profiling—can reveal tumour characteristics that standard testing may miss.

  • 03.

    Biomarker-Matched Treatments

    Some treatments are designed to target specific tumour alterations, such as EGFR amplification, BRAF mutations or TERT promoter mutations.

  • 04.

    Personalized Treatments

    Personalized vaccines and other patient-specific therapies can be designed using the molecular and immune characteristics of an individual tumor.

  • 05.

    Innovative Treatments

    Emerging approaches include CAR-T and CAR-NK therapy, oncolytic viruses, checkpoint inhibitors and other experimental immunotherapies.

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